Name a systemic disease commonly associated with intermediate or posterior uveitis.

Name a systemic disease commonly associated with intermediate or posterior uveitis.

• A. Diabetes mellitus
• B. Hypertension
• C. Sarcoidosis or HLA-B27 associated spondyloarthropathies
• D. Osteoarthritis

Answer: (C)

In intermediate or posterior uveitis, look for systemic inflammatory or granulomatous diseases that commonly involve the eye. Sarcoidosis is a classic example—it's a granulomatous disease that often affects the eye, producing inflammation in the vitreous and posterior segment. HLA-B27–associated spondyloarthropathies (like ankylosing spondylitis and related conditions) are another systemic group known for ocular inflammation, and while anterior uveitis is most typical, they can be associated with posterior or pan-uveitis in some cases. Diabetes mellitus, hypertension, and osteoarthritis are not characteristic systemic associations for this pattern of uveitis; they’re more linked to noninflammatory retinal changes, vascular problems, or degenerative joint disease rather than inflammatory eye involvement.

In intermediate or posterior uveitis, look for systemic inflammatory or granulomatous diseases that commonly involve the eye. Sarcoidosis is a classic example—it's a granulomatous disease that often affects the eye, producing inflammation in the vitreous and posterior segment. HLA-B27–associated spondyloarthropathies (like ankylosing spondylitis and related conditions) are another systemic group known for ocular inflammation, and while anterior uveitis is most typical, they can be associated with posterior or pan-uveitis in some cases.

Diabetes mellitus, hypertension, and osteoarthritis are not characteristic systemic associations for this pattern of uveitis; they’re more linked to noninflammatory retinal changes, vascular problems, or degenerative joint disease rather than inflammatory eye involvement.